Friday, July 24, 2009

Teeny Tiny Someone

So, one gestational sac with a yolk sac. (It's too early for cardiac activity, but I have an appointment for next week and we should be able to see something then.)

All I could think of was that if there were two I would have had a back-up. It is just such a measure of how much loss and failure and disappointment come into play with infertility treatments that I couldn't even muster up some genuine enthusiasm for what is actually normal. And the crazy thing is, I quite emphatically don't want twins. I can understand why it's so appealing after IVF - two for the price of one! - to get even more of what you were hoping for. But the possibility of added complications, especially at my "advanced" age, seriously frightens me.

Anyway, even though I never wanted two take-home babies, I did like the idea of a spare in there, just in case. Which is horrible, because it assumes that the odds are so bad that one by itself doesn't have much of a chance, that something drastic will happen. And I know (really, I do) that it's enough that there is one, that it seems to be doing well so far, that hoping for a back-up is ridiculous when there is still every reason to just go ahead and hope for one that's successful. As long as I'm just hoping, might as well hope for what I really want, right?

If I weren't so nervewracked by by infertility I would be amazed that I have seen my child at such an early stage. I wish I could blithely assume that this is my baby, that in March I'll get to meet this little whitish circle. Shouldn't it feel incredible to be able to watch these earliest moments of your own child's life, to see and know and verify such a teeny tiny existence?

Instead, I'm bracing myself for the next scan, hoping for a good heartbeat and the idea that this one might actually make it.

Monday, July 20, 2009

Limbo

My first meeting with the maternal-fetal medicine specialist (which is maybe just the new-fangled thing to call a perinatologist?) was mostly just that - a meeting, in which we met. We chit-chatted about my history and what her general recommendations would be, with a lot of "if and when", since it's obviously so early. I appreciated that she didn't try to placate me with a lot of reassurance.

She reviewed my protein-S deficiencly results and thought we should retest and look at uterine blood-flow doppler before assuming that I need to switch to lovenox. My hematologist has me on low-dose aspirin until 9 weeks, then lovenox and monitoring. I know that he feels it's better to be on the lovenox just in case, and at this point I am leaning that way, too. So, I have a few weeks to think about it, and maybe the next round of bloodwork will reveal something new, but in general I am willing to err on the side of "don't #2@*% this up."

Other than that, I have nothing. I have no symptoms, no hunches, no news - just me waiting for that first ultrasound. The one good thing I found out from the MFM is that I can still go on my August trip, so at least I don't have to cancel our vacation. I do have to wear compression stockings on the plane, but I should probably do that anyway for my spider veins.

I have been tired, but I don't even have the sore progesterone boobs that I usually get regardless of the outcome of a cycle. I have no nausea, no headaches, no vivid dreams. No overwhelming sensitivity to smell, no cravings. My bras still fit, my pants aren't too tight. Although, to be honest, I'm only wearing the "IVF pants" now - regular pants have been at the far end of the closet rod for a loooooong time.

My OB wants to see me on Friday, but I think that will still be too early for any kind of scan. Done with betas and not ready for ultrasounds. Early limbo.

Thursday, July 16, 2009

Second Beta

I'm still not sure how beta numbers really work when multiple embryos are transferred. It seems like any combination of thriving and failing can produce a vast array of results. But, that said, my numbers more than doubled, to 756. Here's the chart:


So, who knows? But for now, things are good and I suddenly have a slew of appointments with a new MFM, my hematologist, my acupuncturist and - of course - a mani/pedi just to celebrate!

Believe me, I of all people KNOW that this is just the beginning. I'm not telling anyone but my husband (and you!) for a good long while. But it's something, and for now I'm so grateful.

Tuesday, July 14, 2009

Inbox

It's easy to love your clinic after a positive HPT. But can I just say that they have been so kind to me, so helpful and so understanding. After my late loss a few months ago the RE called me several times in the evenings to discuss my case and gave me great referrals to specialists. The coordinator checks and replies to emails even on the weekends, and has always given me a few samples of Follistim to offset the costs of my heavy-duty stim cycles.

And now, this email from her:

Hi!

I’m not really supposed to give you the final call until we see your second beta level….which is why I’m emailing and not calling (things echo in here so much….).

I was excited for you though…your first beta is 329. So far, so good! Continue your medications and I will call you on Thursday to let you know how things are looking.

Congratulations and I’m sorry about being impersonal with the email!


Sweet, right? Waiting until Thursday would have been torture.

In any case, 329. Which is high, even taking into account the fact that I tested a day late since I was out of town. Not that I'm questioning my decision to transfer three embryos - yet, anyway. There are so many hurdles between now and the possibility of then that I'm not even going to think about any of it yet. First things first - or, in this case, second things (next beta) first.

Thanks for all of your lovely comments, too - it meant so, so much to me. Of course, after my laptop died my dad had offered the use of his computer, but I was too nervous to use it while everyone was around. I would wait until they were all asleep and sneak back into the family room to check my reader. It was so wonderful to feel cheered on and congratulated in the wee small hours!

Saturday, July 11, 2009

Shhh

Am visiting parents, laptop crashed, have no privacy, pee stick postive.

Lab tests Tuesday and Thursday.

Yikes!

Monday, July 6, 2009

Chill, Baby

Two of my embryos made it to freeze. I have to say, it never occurred to me that I would have anything left over.

I'm also not sure how I feel about it - two lesser-quality embryos sitting there, waiting. If this cycle doesn't work, I would prefer to do another (pre-paid) fresh one than rely on two slow-poke leftovers. I'll have to go back and read my plan to see if I am required to use the frozens first. If so, I am screwed out of another fresh cycle, since my plan runs out in September.

But, at the same time, in researching CGH I learned all too well that the best-looking embryos are not always the normal ones. In fact, it seems more often than not that the normals are the medium=good ones. Of course, there are a million reasons that this is not statistically reliable outside of that particular testing. For one thing, many people who choose CGH already have a history of abnormalities.

I would have loved to know for sure that I had a genetically normal embryo. And if I go through this again, I may opt for the testing after all. But there seems to be a lot of stress attached to the process, in terms of the additional wait, the high instance of "no result" reports, surviving the thaw, worrying about mosaicism. We decided to just cross our fingers and hope for the best - not very scientific, but since I still have to worry about whatever it is that happened in my last second trimester, we figured we'd save the money for all the fancy specialists that our insurance won't completely cover.

For now I know that if I DO get pregnant, I am going to do amnio as soon as possible. Once upon a time I was so low-intervention that I didn't even take tylenol unless something drastic happened. Now, just get me as much information as possible. If things go awry, I want answers.

In the meanwhile, I'll be traveling at the end of the week, so I'll have to bring my pee-sticks with me. Do you think anyone has ever POAS in one of those little airplane bathrooms?

Saturday, July 4, 2009

0 to 100

So, this is my 100th post. Which may a cause for celebration, but I have some better 100s today.

100% of my embryos made it to day 5. When the doctor came in to talk about how many to put back he was so excited for the good quality that I actually felt a little zip of hope run through my veins. I asked him if he could surgically remove it, but he seemed to think it was a good thing.

We put back the 3 best ones. The whole time we were deliberating on the number to transfer, I was thinking of Sky and Wombded, the opposite ends of the transfer spectrum. Both made really well-considered choices about the number to transfer for their own circumstances, and I am just hoping that it works out as well for me. It's always scary to think about having a pile of babies, but it's also a matter of being realistic about the chances of even getting pregnant. The doctor and I talked a lot about success rates, twins, and SR. With three embryos, my chances of triplets are about 1.5% and my chances of just one are only about 30%.

Still, the fact is, embryo quality has a lot to do with success. Many clinics use an embryo-rating system of an overall number grade followed by two letters. The number describes the outer shell, cavitation and expansion. The letters describe the inner cell mass (the baby) and the outer cells (the placenta). Which makes it easy to see why a "A" baby cells and "D" placenta cells would be bad.

Of course, my clinic has their own special system which involves an overall number rating (1-6) and a 1-100 score that includes inner and outer cells, some kind of enzyme released into the culture medium and a lot of visual assessments by the embryologist. Anything under 70 doesn't really have a chance. We looked at the low-res images of the embryos and they showed me the blob of inner cells and the rings of outer cells. These weren't nice clear pictures like the ones from IVF websites - they were sort of like security-video images.

Anyway, we put back an 87, a 95 and - believe it or not, from these old-lady ovaries - a 100. Now, how am I supposed to keep from thinking this has a chance?

Hope - 0 to 100, just like that.